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High first dose quinine regimen for treating severe malaria.

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It can be used by injection or by tablet and is as potent by either route.

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In 2010, the FDA reiterated its warning and issued a Risk Evaluation and Mitigation Strategy (REMS), which has resulted in a marked decrease in off-label use.

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Osteoarthritis is a chronic disease of the joint cartilage and bone, once thought to result from "wear and tear" on a joint, although there are other causes such as trauma, and metabolic disorders.

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Class 2B means that it has caused cancer in laboratory animals, but that there is only limited evidence of its potential to cause cancer in people.

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To put it differently generics have identical active ingredients and their pharmacological effects are the same, as those of their brand-name equivalents.