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I have been on Topamax for about four years now. I think the drug works however, I have developed Kidney Stones. I guess I am one of the few that do but I did therefore, I am seeking other drugs. As most have stated, my taste changed and anything with carbonation was terrible for the longest time. I eventually pushed through the changes and now everything pretty much tastes the way it should be on the medicine. I have allergies so the headaches I experience are mostly caused by that (which is why I think I have been pushed up to 200mg a day). Just a forewarning to everyone... When they say drink water DRINK!
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I've been using Topamax for about a year now and have not really seen a difference in my pain threshold. I get very shaky when I take a dosage and still experience migraines.
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Concomitant administration of topiramate with other CNS depressant drugs can result in significant CNS depression.
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The Food and Drug Administration warned women of child-bearing age that the epilepsy drug Topamax can increase the risk of birth defects around the mouth.
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Medications have their place, but it is surely good to research on your own, and get second opinions and alternate options.
In topiramate-treated adolescent patients (12 to 17 years) compared to placebo-treated patients, abnormally increased results were more frequent for creatinine, BUN, uric acid, chloride, ammonia, total protein, and platelets.