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This effect is probably important only in people with riboflavin deficiency.
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In addition, colchicine does not have analgesic properties and may be less effective in treating acute flares when given beyond 72 to 96 hours after symptom onset.
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Clostridium difficile associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including Zosyn, and may range in severity from mild diarrhea to fatal colitis.
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