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Five drugs are most commonly used today to treat tuberculosis: isoniazid (INH, Laniazid, Nydrazid); rifampin (Rifadin, Rimactane); pyrazinamide (Tebrazid); streptomycin; and ethambutol (Myambutol).
Although FIND has negotiated concessionary pricing for public-sector programs in low-income countries and is working to further lower the costs of testing, the costs of instruments and tests will still be considerably higher than those for microscopy, which is all that is currently available in peripheral health care settings in many countries.
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Rapid point-of-care detection of the tuberculosis pathogen using a BlaC-specific fluorogenic probe.
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This is important with respect to TB with pregnancy where many of the second-line drugs are teratogenic and need to be prescribed with great caution and the outcome of the treatment with best of the regimens is suboptimal.
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