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My sister is a Parkinsonism sufferer. Her disease is progressive and she needs really good care, a lot of attention and effective medications to support her organism. Sometimes she literally can't move any part of her body and that scares me to death as I don't know if this will come to an end or she'll stay motionless. Sinemet helps me cope with her symptoms reducing trembling, tremor and avoiding these attacks of paralysis. I hope this drug will show off its full potential soon.
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In 1987 Somerset Pharmaceuticals in New Jersey, which had acquired the US rights to develop selegiline, filed a (NDA) with the FDA to market the drug for PD in the US.
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The self-mutilation is often reduced by using restraints.
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The role of transcranial sonography in the investigation of these disorders is described below.
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Similarly, venlafaxine should be stopped for seven days before starting an MAO inhibitor antidepressant.
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Dementia is the most difficult symptom to treat in this setting.
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Parkinson disease is the main entity to be considered.
In primates it has been shown that dyskinesia is not induced in healthy controls at the same dose that induces dyskinesia in those with less dopaminergic neurons and Parkinsons progression.
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FDA notified healthcare professionals and patients that it is evaluating data from a long-term clinical trial called Stalevo Reduction in Dyskinesia Evaluation - Parkinson's Disease (STRIDE-PD), that may suggest that patients taking Stalevo (entacapone, levodopa, and carbidopa combination) may be at an increased risk for developing prostate cancer.
A generic drug is actually its brand-name equivalent, although it doesnt bear the original trademark and looks slightly different.
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Carbidopa significantly improves mobility and allows them to function relatively normally, at least in the early stages of the disease.
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Sinemet CR (carbidopa-levodopa) sustained-release tablets prescribing information.
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Early treatment can provide years that are virtually symptom-free.
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If treatment with SINEMET continues, patients should be advised not to drive and to avoid other potentially dangerous activities that might result in harm if the patients become somnolent.
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It is a documented fact that these drugs may induce system-wide PLP depletion, representing an RND that is reversed with vitamin B6 administration.
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