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Public Health Issue: The accurate evaluation of active pharmaceutical ingredients (API) and formulation excipients is essential for preformulation assessment and optimization.

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B6 and magnesium), or randomized controlled evidence does not support its use (e.

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On-treatment study assessments were scheduled at the end of weeks 1, 2, 3, 4, 5, 6, 7, and 8 or upon early withdrawal.

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venlafaxine is an antidepressant that inhibits the reuptake of serotonin and norepinephrine

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However, partly because of its low serum protein binding, it is widely accepted that venlafaxine does possess dual uptake blocking properties in vivo, particularly in the upper range of dosage.

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Review of the results from clinical studies on the efficacy, safety and tolerability of mirtazapine for the treatment of patients with major depression.

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Decreased appetite (reported as treatment-emergent anorexia) was more commonly observed in venlafaxine hydrochloride extended-release capsules treated patients versus placebo-treated patients in the premarketing evaluation of venlafaxine hydrochloride extended-release capsules for MDD and SAD (see Table 6).

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ER was less than 10% at any dose compared with 0% on placebo.