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Qsymia is a combination of two FDA-approved drugs: phentermine, a fifty year old appetite suppressant, and topiramate, used to treat epilepsy for the last nineteen years and migraines for the last eight.
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The prescriber should be aware that these data were obtained when topiramate was added to concurrent antiepileptic drug therapy and cannot be used to predict the frequency of adverse reactions in the course of usual medical practice where patient characteristics and other factors may differ from those prevailing during clinical studies.
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In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof.
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The safety and efficacy of Qsymia were evaluated in two multicenter, phase 3 trials that included severely obese patients (the EQUIP study), and overweight or obese patients with at least two weight-related comorbidities, such as hypertension, hypertriglyceridemia, type 2 diabetes, or central adiposity (the CONQUER study).
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