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Banja UVOD-test fizickim optereenjem u pacijenta sa Sy WPW ima svoja ogranicenja u pojavi promena na EKG koja imitiraju miokardnu ishemiju te se javljaju lazno pozitivni testovi.
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Erythropoietin reduces anemia and transfusions: a randomized trial with or without erythropoietin during chemotherapy.
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Two New Drug Applications (NDAs) were submitted to the FDA for regulatory approval during the quarter.
Denis Cournoyer of McGill University, the lead author of the Canadian paper, said the incident showed the need for better surveillance of side effects after drugs reach the market.
As such, distinct glycosylation variations between the EPO products shown by different isoforms can also contribute to the differences in potency.
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Randomized controlled trial of Darbepoetin Alfa administered as a fixed or weight-based dose using a front-loading schedule in patients with anemia who have nonmyeloid malignancies.
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This is commonly addressed by using multiple analytical methods that rely on different mechanisms to separate the leachables from the drug formulation.
In 2013, an Indian generic drug maker and its partner received regulatory approval to market biosimilar bevacizumab in India.
They questioned why CMS would impose dose limitations when the drug label does not.
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If it is determined that a patient can safely and effectively administer Aranesp ä at home, appropriate instruction on the proper use of Aranesp ä should be provided for patients and their caregivers, including careful review of the “” insert.
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Potentially adverse effects may be due to induction of neoangiogenesis by the hormone, since erythropoietin increases inflammation and ischemia-induced neovascularization by enhancing the mobilization of endothelial progenitor cells.
Inflammation-induced synthesis of hepcidin plays a crucial role in macrophage iron retention, which underlies the anemia of chronic disease by limiting the availability of iron for erythroid progenitor cells.
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