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The carcinogenic potential of tacrolimus ointment beyond immune suppression: a hypothesis creating case report.
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Simplified diagram illustrating the points of action of immunosuppressive drugs.
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Calcineurin then dephosphorylates the transcription factor nuclear factor of activated T-cells (NF-AT), which moves to the nucleus of the T-cell and increases the activity of genes coding for IL-2 and related cytokines.
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For all patients standardized questionnaire for demographic and clinical data, specially for history of alcohol dependence and alcohol abuse, was used.
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Wacke R1, Karasch I1, Mueller SC1 1 Institute of Clinical Pharmacology, University of Rostock, Rostock, Germany Aims: Therapeutic drug monitoring is widely accepted for neuropsychiatric drugs.
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In this case the increase in active metabolite A 2 (following the previous example) produces an increase in the drug's effect.
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