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I was put on hydrochlorothiazide by my urologist for the prevention of kidney stones. I was a regular producer of a stone every 12-18 months prior to starting hydrochlorothiazide. It has been 5 years and counting without a kidney stone. That's the up side. The down side is after about 6 months on this medication I had my first bout with gout. Ever since then I regularly have to deal with gout about every other month. I feel like I traded one type of severe, less often pain for a lower, more recurring pain.