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After working around or within the methadone treatment camps, DuPont gave up trying to convert proponents of the "methadone philosophy" to the benefits of treatment with antagonists.

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Its long duration of action means that naltrexone can be given two or three times per week, but daily administration is usually preferred, both because of developing a regular habit of use and of creating a higher blockade.

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Mary and Jack had been married 8 years, and Jack was considering leaving the marriage, when the staff at the detoxification unit referred them to the BCT program.

Naltrexone is a pure opioid antagonist originally marketed by DuPont as Trexan for the treatment of opioid dependence, and later as ReVia for the treatment of alcohol dependence.

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