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This combination medication contains a nonnucleoside reverse transcriptase inhibitor (NNRTI) and 2 nucleoside reverse transcriptase inhibitors (NRTIs) (antivirals), prescribed for HIV-1 infection in naive adults.

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Effects of grapefruit juice on the pharmacokinetics of pitavastatin and atorvastatin.

Of relevance to this article, the locations of MDR1 at the luminal surface of enterocytes enabled the back transport of cellularly absorbed drug and at the bile canalicular membrane of hepatocytes facilitated drug extrusion from cytoplasm into bile.

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In the present study total leucocyte count, differential count of neutrophils, lymphocytes, eosinophils, and absolute eosinophil count were carried out at both visits and the results were compared between the groups.

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