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Although indomethacin is the NSAID traditionally chosen for acute gout, most of the other NSAIDs can be used as well.

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When the treated cells are washed with a colcemid-free solution, colcemid diffuses from the cell and mitosis resumes normally.

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Exacerbation of gout following therapy with probenecid and colchicine may occur; in such cases additional colchicine or other appropriate therapy is advisable.