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Overall survival time was defined as the number of days from the first day of treatment until death or the last tumor assessment.

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However, since tolterodine and DD 01 have similar pharmacological effects, the net activity of tolterodine is expected to be similar regardless of CYP2D6 metabolizer status.

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EGFR mutation specific immunohistochemistry is a useful adjunct which helps to identify false negative mutation testing in lung cancer.

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If carmustine is administered intravenously, side effects may include nausea and vomiting, fatigue, respiratory problems, and lung scarring (pulmonary fibrosis).

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The effect of extent of resection on time to tumor progression and survival in patients with glioblastoma multiforme of the cerebral hemisphere.

Both smokers and nonsmokers whose lungs are scarred from recurrent lung diseases, such as pneumonia or tuberculosis, are also at increased risk, particularly for bronchoalveolar lung cancer.

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More than 8 prospective trials have evaluated gefitinib or erlotinib monotherapy in EGFR-mutated NSCLC.

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We thank Fiona Boswell and Hannah FitzGibbon from Complete Medical Communications who provided editorial support funded by AstraZeneca.

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Other irreversible inhibitors that target both EGFR and the related protein ErbB2 are also being tested in clinical trials of NSCLC as well as breast cancer.

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PD)-1 with its ligands PD-L1 and PD-L2 has been investigated as a target for cancer immunotherapy ().

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