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I've had hyperthyroidism for 3 years now. Being hyperthyroid however without clear diagnosis for quite some time was a trial for me. I had many different symptoms that used to make my life a lot more difficult but I was trying hard to be patient while my doctor was carrying out different tests to define my condition. Then when the diagnosis was settled he started testing different medications to select a better treatment for me. I tried to be patient in spite of constant panic attacks, insomnia and high heart rate. But nothing seemed to help. Due to general exhaustion I looked rather gloomy - greyish skin, dull hair, skinny and passive. I couldn't work and my health worried me greatly. Then finally my doctor suggested Carbimazole. I started on a lower dose and had regular blood tests, so after about three months we found the ideal dosage for me and half a year later I stopped taking it. I am absolutely happy with the way Carbimazole worked for me and I hope the effect stays stable for long. But anyway if my thyroid level goes high again I will start on Carbimazole as it is very effective and showed no side effects.
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However, it is important to always be mindful of the potential the treatment itself has to cause or exacerbate PIH by causing irritation.
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This is to say that if a treatment group is defined as having received the treatment for a given span of time, in this case six months, then this six month period is “immortal time”, during which time an event, in this case death, cannot have occured in order for a patient to be included in this time-defined group.
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Treatment with methimazole before RAI therapy is beneficial because it does not affect the overall efficacy of RAI and pretreated patients have lower thyroid hormone levels than patients treated with RAI alone.
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