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I've had restless leg syndrome for about 15 years and have tried several medications. Gabapentin worked most nights, but left me practically catatonic the next day. Klonopin did nothing to help my symptoms. Requip made me feel like I was going insane, and really scared me. I gave Mirapex a high rating because it has completely eliminated all my symptoms. Unfortunately, I have severe nasal congestion as a side effect which also keeps me up all night. If I don't take it, I can breathe, but my legs are jumping and jerking all night. If I do take it, my nose feels like it's filled with cement. Either way I can't sleep. I guess it's back to the doctor to try something else.
I've been using Pramipexole for several years, gradually increasing the dosage over the years to 0.5 mg. I've found it to be somewhat effective although I still have some involuntary kicking in my sleep, and onset of restless legs while driving for extended periods.
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