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over http://www.cheapairmax90mens.com/ ,
the constraining bone is subjected to expansion strains as indicated by the Von
Mises strains colored map reported in the right hand side of figure 3. The color
scale utilized for this map is the same of that reported in figure 2, namely,
the adaptive window of bone physiology where healthy bone growth and induction
corresponds to the colors yellow and green and blue and red to bone
reabsorption.
The surrounding bone is subjected to a healthy bone physiological deformation
for a distance equivalent to the implant diameter. In this toroid volume
surrounding the implant, then, it would be expected an osteoinductive effect and
more rapid implant osteointegration.

A micro Computer Tomography has confirmed these expectations.

Figure 5 shows the micro CT of these volumes.

In the upper part of the figure is reported the external volumetric
reconstruction of the bone and implants while in the lower part it is shown the
3D reconstruction of the volume surrounding one implant.

The Bone Implant Contact (BIC) and the relative bone density have shown
similar characteristics at cortical (a) and medullar levels (b) indicating a
good implant osteointegration with the original bone. The newly formed bone near
to the implants surprising shows characteristics similar to the previous one
(c), indicating that a biomechanichally stimulating effect of the swollen hybrid
scaffolding material.

Conclusions

It is necessary to develop new technologies in biomaterials field, in order
to obtain scaffolds and bone substitutes that could have a fundamental role in
bone regeneration. It is requested to bone scaffolds to show particular
intrinsic characteristics in order to work as a real bone substitute that
satisfies biological, mechanical and geometrical constrains. Such features
comprise:

Biological requirements - the computed scaffolds must enable cell adhesion
and homogeneous distribution, growth of regenerative tissue, and assist the
passage of nutrients and chemical signals. This achievement has been attained by
controlling the porosity of the scaffold; Mechanical requirement - the estimated
scaffolds must preserve the mechanical and toughness properties that allow
osteoblasts colonies to experience physiological and bioactive controlled
deformations. This has been achieved by properly modifying the hybrid
ceramo-polymeric compositional ratio (in our case, 10% by volume of amorphous
nano-silica).

Combined clinical observation of traditional implant behaviour will be used
to validate the biofidelity of the FEM models, while comparison between in vitro
and computer aided simulation of osteoblast colony growth can then allow us to
explore many novel ideas in modelling cheap air vapormax ,
design and fabrication of new nanostructured scaffolds with enhanced
functionality and improved interaction with cells. This turns particularly
useful in designing and directly manufacturing complex bone tissue scaffolds.

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