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Pharmacologic therapy for patients with chronic heart failure and reduced systolic function: review of trials and practical considerations.

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One major theme in this literature is concerned with the potentially adverse effects of acute caffeine intake on heart function.

The rationale for using fixed-dose combination therapy is to obtain increased blood pressure control by employing two antihypertensive agents with different modes of action and to enhance compliance by using a single tablet that is taken once or twice daily.

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Effect on insulin sensitivity of angiotensin converting enzyme inhibitors with or without a sulphydryl group: bradykinin may improve insulin resistance in dogs and humans.

Yet, high blood pressure can start without any other signs or symptoms and persist undetected for years if not measured.

However, on a mole-for-mole basis, the hypocalciuric effect of orally administered potassium overrides the hypercalciuric effect of dietary sodium (Morris et al.

The protocol was approved by the ethics committee of our institution, which recommended an open-label design of the study, considering the pilot nature of the trial, the severity of the treated diseases, the high incidence of infectious complications, and the potential hypotensive effect of the intervention.

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Enalapril may be used to treat essential or renovascular hypertension and symptomatic congestive heart failure.

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