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Caution should be exercised in patients with history of liver disease, kidney problems, diabetes, irregular heartbeat, low blood potassium levels, mental disorders, any allergy, who are taking other medication, elderly, children, during pregnancy and breastfeeding.

The reported cases of TdP were in patients who took large overdoses of quinine sulfate or those who took it with other drugs that prolong QT.

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Normally, the extra oxygen needed during exercise is supplied by a faster and a more voluminous blood flow through the coronary arteries.

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Ranolazine also decreased fasting glucose and PPG and fasting and postprandial glucagon levels.

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In an acute cardiovascular disease event where the patient is suffering from or at risk of suffering from renal insufficiency, the use of such concentrations of ranolazine can result in higher ranolazine plasma levels.

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Nitrates, immediate or sustained release, are effective at relieving symptoms, but have never been shown to improve outcome.

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Follow your doctor's orders or the directions on the label.

These elevations were observed without evidence of renal toxicity (see PRECAUTIONS and Laboratory Tests).

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The increase in fatty acid uptake and oxidation is exacerbated with the use of PPARα ligands in these mice ().

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