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Last year I have traveled to Madagascar. It is the biggest island in the Indian Ocean and the biggest island in the whole world. The flora and fauna are astonishing there, as well as the range of different bacteria and infections one can catch there. Before the trip I have taken Quinine to protect me from malaria as it is a very nasty disease to catch. I started on Quinine two days before the departure and continued for several days after I came back. I believe it's due to Quinine that I have not contracted malaria, neither have I had any side effects connected with taking the medication. It is very important that such vital drugs that help prevent life-threatening diseases do not create major difficulties for people who have no other way out but taking them.

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Reabsorption of quinine is increased when urine is alkaline; rate of renal excretion of the drug is doubled when urine is acidic compared with when urine is alkaline.

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In some cases, people who have been given quinine can develop a condition called cinchonism, which is related to the dosage they receive.

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The crude quinine sulphate is redissolved in water, decolorised with charcoal and recrystallised until cinchonidine and cinchonine are reduced to the required percentage Quinine may be obtained from the sulphate by precipitation with alkali, washing and drying.

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