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Under certain circumstances if unvaccinated health-care personnel cannot get vaccinated and who have intensive contact with oropharyngeal secretions of infected patients and who do not use proper precautions should receive anti-infective prophylaxis against meningococcal infection (i.

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Rifampicin and rifabutin are such potent enzyme-inducing drugs that an alternative method of contraception is always recommended.

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Appropriate administration materials should be composed of glass, polyolefin, or polyethylene to avoid excessive loss of product and diethylhexylpthalate (DEHP) extraction.

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Thus, induction of p-glycoprotein could explain the rifampicin-digoxin interaction.

Mutations in the rpoB gene, encoding the β subunit of the bacterial RNA polymerase, have been strongly associated with rifampicin (RMP)-resistant phenotypes in multiple study populations.

In 1972, a retrospective study was published looking at 200 patients previously treated with rifampicin.