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This may result in the activation of c-Jun-NH2-kinase (JNK) and ultimately apoptosis via Bcl2 suppression and caspase-3 activation.
Gout is a metabolic disorder characterized by the accumulation of uric acid in the blood stream or joint cavities.
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Hard to tell if the hot flashes are spironolactone or perimenopause, but I didn't get hot flashes until I started taking spironolactone and they can be very bad.
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The trial was discontinued early, after a mean follow-up period of 24 months, because an interim analysis determined that spironolactone was efficacious.
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Vitamin C deficiency may occur but it is not a hallmark symptom of the disorder.
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Cyclosporine and cyclosporine (modified) are also sometimes used to treat Crohn's disease (a condition in which the body attacks the lining of the digestive tract, causing pain, diarrhea, weight loss, and fever) and to prevent rejection in patients who have received pancreas or cornea transplants.
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