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Local irritation in the esophagus can cause symptoms that vary from indigestion, like chest discomfort and abdominal pain, to coughing and wheezing.

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This guideline intends to show the place of both new and established treatments in the wider care pathway for Crohn's disease.

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Experience from Japanese Mega Study (JMMS) Koji Nakada, Michio Hongo, Shigeru Harasawa, Tetsuya Mine, Iwao Sasaki, Kei Matsueda, Motoyasu Kusano, Nobuyoshi Hanyuu, Chikashi Shibata There are some sex difference in some FGID in their pathophysiology and responses to medical interventions.

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