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Ursodiol is the best medication on the market for biliary cirrhosis treatment. I have been a sufferer of primary biliary cirrhosis for more than six years when I was first prescribed with Ursodiol about a year ago. A few weeks later I have undergone a comprehensive testing and the results indicated that my AMA was negative! Then my doctor decided to put me off Ursodiol and see what happens. But the observations showed it was too early to stop taking Ursodiol so I'm on it again and it still helps. In general the medication is fantastic. Hope I'll be able to cope without it soon.


I was dx PBC-Stage 2 Feb 08 and started URSO. I was sent to Baylor a few weeks later and their tests indicated I had a negative AMA! They asked me to stop taking URSO to see if weight loss alone improves the condition. I was off URSO for 4 months and lost 25 lbs. My AMA count is higher now than ever, so I am going back on URSO this morning. It is very obvious to me that the URSO put my antibodies to sleep while I was on the drug. That is why my doctor put me back on it today.