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In vitro studies in animals also suggest that sertraline is a potent and selective inhibitor of neuronal serotonin reuptake and has only very weak effects on norepinephrine and dopamine neuronal reuptake.

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Hypomania induced by sertraline, a new serotonin reuptake inhibitor.

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On the other hand, the combination of 45 mg DL-tryptophan (a synthetic variation of L-tryptophan) per pound of body weight (a relatively high dose) with zimelidine, a drug with a similar action to sertraline, did not cause these side effects in another trial.

Medication Guide about "Antidepressant Medicines, Depression and other Serious Mental Illness, and Suicidal Thoughts or Actions: is available for Sertraline.

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This time around (three months ago), Walgreens gave me the Northstar generic.

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Also, there are drugs that never held patents, and in some countries patents are just not enforceable.

Generic means using a different name for the same ingredients.

Serotonergic Drugs: see CONTRAINDICATIONS, WARNINGS and DOSAGE AND ADMINISTRATION.

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In vitro studies have shown that sertraline has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT 1A, 5HT 1B, 5HT 2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs.

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It works by increasing the activity of a chemical called serotonin in the brain.

There was a significant and positive correlation between baseline 5-MTPM levels and treatment response at four weeks, indicating that higher levels of 5-MTPM before treatment were associated with a more favorable response.

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