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Studies are mixed as to whether EPO helps reduce symptoms of rheumatoid arthritis.
The effect of HRT on the risk-reducing properties of tamoxifen is a controversial issue.
Soy isoflavones, estrogen therapy, and breast cancer risk: analysis and commentary.
Endoxifen HCl, the active metabolite of Tamoxifen, ia a potent and selective estrogen receptor antagonist.
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In the Eastern Cooperative Oncology Group (ECOG) adjuvant breast cancer trial, Tamoxifen or placebo was administered for 2 years to women following mastectomy.
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Practically speaking, a biomarker with a PPV of 10% implies that ten surgical procedures would be required to identify one case of ovarian cancer; the remaining nine surgeries would represent false-positive test findings.
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Patients assigned to 5 years of tamoxifen experienced significantly longer breast cancer event-free survival and overall.
it is not known whether the fracture rates seen are due to a protective effect of tamoxifen
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Structure-activity relationship studies shoved that by removing that group of tamoxifen agonistic activity in the uterus was significantly reduced, but not in bone and cardiovascular system.