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I had 2 laminectomies at L4/L5 and the first one failed in 6 years, the second has been holding its own, but scar tissue has formed and the disks above and below are impinging the nerve slightly. After 2 years of trying every muscle relaxer my pain management doctor used Baclofen 10mg 3 x daily. I noticed improvement within a week and now in combination with Cymbalta 60mg daily, I can walk on my right leg without having to sit down every 5 minutes. I don't have any side effects from Baclofen like Flexeril where I would drag all day and then the next day feel hung over and could not get off the couch.






















I too suffer from back and leg pain. I have had 3 surgery's pain stimulator implanted as well. The back and leg spasms have gotten so bad starting around 2pm till I wake in the morning. Some nights I'm up all night. Started medicines as directed 1st time. But had some very strange reactions. Like I couldn't breath, almost paralyzed, then hives. So I stopped. But the spasms became so bad, I just couldn't bare to go on anymore this way. I started again taking 1/2 a pill 2 times then 3 times. So far I just itch, I can deal with that. It is helping with spasms, that is the best part of all. And OMG if it also helps with migraines, that would be even better, since I am also being treated for them as well. Life can be unbearable. Thanks for help.

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Defining the Therapeutic Role of Local Anesthetic Sympathetic Blockade in Complex Regional Pain Syndrome: A Narrative and Systematic Review.

For patients receiving intrathecal baclofen, importance of keeping scheduled refill visits and of recognizing early signs and symptoms of withdrawal.

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The dose of intrathecal baclofen will be different for different patients and will depend on the type of muscle tightness that you have.

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Intrathecal baclofen treatment of dystonia in reflex sympathetic dystrophy.

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Some of the CNS and genitourinary symptoms may be related to the underlying disease rather than to drug therapy.

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Positive prognostic factors include the extent of mobility before the operation, underlying strength and balance, availability of regular physical therapy after SDR, and the patient's motivation and ability to undertake the rehabilitation process.

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The child should be evaluated by a communication enhancement center to guide speech and language treatment and the use of communicative devices.

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Nevertheless, it can be speculated that baclofen may play a therapeutic role through the effective blockade of all types of reflux events as well as the nonspecific antitussive effect.

Another neurosurgical treatment is that of selective dorsal rhizotomy, which may be beneficial in both the short term and long term to treat velocity-dependent spasticity.

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The purpose of this study is to determine if baclofen dose-dependently decreases marijuana's direct effects and symptoms of marijuana withdrawal and thus decreases marijuana relapse in our laboratory model.

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Some clinical characteristics of the advanced intrathecal baclofen withdrawal syndrome may resemble autonomic dysreflexia, infection (sepsis), malignant hyperthermia, neuroleptic- malignant syndrome, or other conditions associated with a hypermetabolic state or widespread rhabdomyolysis.

This is especially important for certain patients who are at greater risk (eg, spinal cord injuries at T-6 or above, communication difficulties, history of withdrawal symptoms from either oral or intrathecal baclofen).

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Tests showed that the drug performed poorly for this use, but its worth as an antispasmodic was discerned.

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