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My doctor started me on Metoprolol after cardiac ablation for Atrial Fibrillation. It actually made my heart rate worse. I was waking up at 2am-5am every single morning in tachycardia of 115-148 bpm. I stopped taking Metoprolol, and have been in normal sinus rhythm ever since. I am glad it works for most, it just did not work for me. Atrial Fibrillation and/or tachycardia is horrible, and they have got to come up with something new for us sufferers soon.
I have been taking Toprol XL for 10 years. I began with 50 mg per day, and am now at 200 mg per day. Unlike another report posted here, I am sleeping better while taking the medication. The only two side effects I've experienced are shakiness and nervousness when I miss a dose by even a few hours and vague aural hallucinations (hearing things) while on the verge of falling asleep. I've seen the hallucinations reported by other toprol users on other sites.
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Support for work on the manuscript was provided by the University of Michigan Department of Clinical Affairs.
Rheumatic heart disease with metoprolol: a systematic review.
Even Apple Cider Vinegar has only temporary effects on me.
Harvey et al state that with antidepressant withdrawal (though they are probably talking about immediate withdrawal, not months afterwards) you will have a loss of glial glutamate transporters and a buildup of synaptic glutamate, just like in depression, but also an increase in glutamate NMDA receptor density.
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In 2008, Novartis' generics unit Sandoz recalled its version on manufacturing troubles; early last year, KV Pharmaceutical stopped making generic Toprol as it deals with an FDA investigation.
Wellbutrin, the antidepressant, was not the equivalent of the brand-name product and said it would take a closer look at how well generic companies were making extended-release drugs.
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For mild cases, lifestyle changes (such as avoiding certain foods), elevating the head of your bed, and taking over-the-counter medication may be enough to reduce symptoms.
Some medicines used to treat severe allergies may also not work as well while you are using Toprol XL.
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