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Nonhealing ulcers, cuts leading to gangrene and amputation Kidneys HTN, renal failure Neurology Paresthesias, neuropathy Diagnosis Serum glucose above cut-off points after meals or when fasting; once therapy is begun, serum levels of glycosylated Hb are measured periodically to assess adequacy of glucose control Management Therapy reflects type of DM; metformin and triglitazone have equal and additive effects on glycemic control Prognosis A function of stringency of glucose control and presence of complications.

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To put it differently generics have identical active ingredients and their pharmacological effects are the same, as those of their brand-name equivalents.

That is if you took regular Metformin and had a big GI bleed from it then you might be able to sue especially since they failed to give adequate warning to people using it.

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Which of the following are potential side effects of metformin?

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Because most patients with type 2 diabetes continue to secrete some amount of endogenous insulin even in the late stages of the disease, initial insulin therapy usually involves a basal-only regimen aimed at suppressing overnight hepatic glucose production, thereby lowering glucose levels during sleep and between meals.

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