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This is my 3rd month on Tizanidine. Was on 2mg four times a day for severe low back and neck spasms and pain from an injury sustained while in Iraq. Also been on many types of relaxers and other pain medicines with no significant relief until my doctor wrote me a prescription for tizanidine. Since I've been on it daily activities have increased, taken 2-6 hour road trips with no major problems, and been able to increase my nightly naps and turn those into dream filled lapses in reality for close to 6 hrs/night! Cut Ambien use in half. Now on 4mg three times a day. The only negatives I have for this medicine is it doesn't last long enough, dry mouth is bad, dreams are sometimes too vivid causing nightmares, and hallucinations have occurred due to user error. Follow doctors orders while using this medicine.
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Single-Dose, Phase 1b, Multicenter, Open-Label Study to Assess the Pharmacokinetics, Safety and Tolerability, and Pharmacodynamics of Tizanidine at 4 Different Oral Dose Levels in Pediatric Subjects 2 to 16 Years Old With Mild to Moderate Spasticity Due to Cerebral Palsy.
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The imidazoline chemical structure of tizanidine is related to that of the antihypertensive drug clonidine and other alpha2-adrenergic agonists.
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Tizanidine (tye zan' i deen) is an imidazoline derivative and is a centrally acting muscle relaxant used for therapy of acute muscle spasms and chronic spasticity.
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Treatments to try and reduce spasticity include exercise, and drugs to try and decrease the muscle tone.
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