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No definitive serious adverse event reports of distant spread of toxin effect have been associated with Botox for blepharospasm or for strabismus at approved doses.
The authors concluded that in this pilot study, injection with onabotulinumtoxinA was shown to be of possible usefulness to relieve the pain and improve function in Morton neuroma.
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For the analysis of each formulation, 8 different samples of the topical diltiazem, each approximately 1 g in weight, were taken from pre-specified locations within the compounded formulation container.
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Botox can be used to reduce spasticity or excessive muscular contractions to relieve pain; to assist in posturing and walking; to allow better range of motion; to permit better physical therapy; and to reduce severe spasm in order to provide adequate perineal hygiene.
Neutralizing Antibodies to Botulinum Toxin: Aetna considers testing for neutralizing antibodies to botulinum toxin experimental and investigational.
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But I wonder if cranial sacral, chiropractic, osteopathy, and other bodywork might be able to release a sphincter spasm more naturally?
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Ratings included brief pain inventory, McGill pain questionnaire, clinical pain impact questionnaire, quantitative skin sensory test, sleep satisfaction scale, and patient global satisfaction scale.
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Internal sphincterotomy is superior to topical nitroglycerin in the treatment of chronic anal fissure: results of a randomized, controlled trial by the Canadian Colorectal Surgical Trials Group.
Heise et al (2005) reported their preliminary experience with the use of botulinum toxin A for the treatment of biceps-triceps muscle co-contraction.
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