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Having suffered from rheumatoid arthritis for more than 20 years I suffered a whole body flare 5 years ago severe enough to almost prevent me from walking. Twenty-six days after being put on Minocin by my doctor at Harvard Medical School I was riding my bicycle 10 miles a day. Minocin is not a "cure" for rheumatoid arthritis. Whenever I have attempted to get off this drug the rheumatoid arthritis has come back within 2 months. But as long as I take it you would never know I have rheumatoid arthritis. Only side effect I've experienced is a grayish blue tint to my skin on my neck and cheeks.