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I've been taking this medicine for a month today. I have seen a significant and favorable drop in my blood sugar however, I've never felt sicker in my entire life. Everyday since starting this I've been nauseous even to the point of vomiting. I find that I now have motion sickness and since I take public transport, I sometimes have to get off the bus to vomit. I always have diarrhea. I sometimes have fever symptoms, chills along with a feeling of being very cold, and terrible headaches. I've also become quite anxious, restless, and moody, which may be a side effect of these side effects. I've lost 12lbs and I find myself eating less which is awesome but I'm ALWAYS nauseous, which is why I have no appetite.