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I also want to say I have been taking it for 3 yrs... And it did help with my depression but my sex life was terrible and trying to get off of it has given worst withdrawals ever... But I really think this medicine affects every person differently.


I take 100 mg. It works but side effects were I was always tired and gained weight. Took Wellbutrin with it when I was taking 50mg. That made me feel close to normal but I got headaches and gained weight. I was good enough with just the Pristiq, but not great. The doctor then added Dextroamphetamine, which now has me feeling normal, like when I was in my 20's. I have motivation, energy, focus, no panic, no depression and once again feel the wide range of emotions as they are meant to feel. I am able to take joy in the small things in life and not dwell on the down sides. My weight has also adjusted back to pre-medication size.