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Effexor XR (venlafaxine): Started at 37.5 for hot flashes but also found that my hair trigger anger and low grade depression were gone. Oh, did I mention the onset of suicidal Ideation I experienced at menopause? Took care of that too. Went up to 150xr a day, but stomach upset, excessive teeth grinding, loss of libido and weight gain are making me go back to 37.5 again. Ended up on the 150 cause of my wicked hot flashes.....but willing to deal w them at 37.5 for the sake of my sex life. I'm afraid to go off of it at 37.5, as it removed the anxiety and despair I realized I have felt most of my life. I encourage many to stay at the lowest dose of any of these drugs; it takes time to figure out which one is good for you. Cheers


Do NOT let your prescription run out or take yourself off Effexor abruptly! I experienced this by accident while waiting for a mail-order prescription to arrive (my doctor was just moving into a new office and didn't have samples available). Within 2 days, I was a wreck emotionally (depressive, sobbing for no reason), cognitively (all over the place, no concentration), and physically (impaired motor coordination among other things). The "brain shivers" a feeling like an electrical current running from the brain down the spine and back again, are very disconcerting! I got samples from my doctor's former office and was noticeably better within hours of 1 dose.